Maintain Joint Health with More Synovial Fluid Production

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Joint maintenance and joint care are key to keep training on schedule. Repetitive stress from competition and conditioning, in addition to everyday wear and tear, impacts even the most athletic horses.1 From racehorses to jumpers, every horse is susceptible to joint damage.

The equine joint is engineered to provide virtually frictionless motion through the combination of a smooth articular cartilage surface as well as lubrication of the cartilage and the synovial membrane.

The synovial membrane of the joint produces a lubricating substance or “joint oil” called synovial fluid. The high levels of hyaluronic acid (HA) in this fluid help lubricate the soft tissues within the joint (boundary lubrication) and to a lesser degree, help lubricate the articular cartilage itself.

Consider using LEGEND (hyaluronate sodium) to maintain joint health and increase lubrication production. LEGEND is pure HA, and helps stimulate the body to create its own natural HA.

LEGEND also comes with the benefit of flexible administration so you can treat the way that works best for your busy schedule. LEGEND delivers the same effective therapy whether given by intravenous (IV) or intra-articular (IA) administration.2 IV administration allows treatment with minimal training disruption versus the stall rest recommended after IA administration. And LEGEND was the first FDA-approved joint therapy available for both types of administration.2

The sooner a horse receives proper joint treatment, the greater the chance of maintaining performance, soundness and longevity.3

Merial is a world-leading, innovation-driven animal health company, providing a comprehensive range of products that focus on disease prevention and overall health and wellness in animals. Merial has three main business areas: pets, farm animals, and veterinary public health, and our health solutions target more than 200 diseases and conditions across a variety of species. Merial employs 6,900 people and operates in more than 150 countries worldwide with over €2.5 billion of sales in 2015. Merial is a Sanofi company. For more information, please see www.merial.com; @Merial.

IMPORTANT SAFETY INFORMATION:
The safety of LEGEND has not been evaluated in breeding stallions or in breeding, pregnant or lactating mares. The following adverse reactions have been reported following use of LEGEND Injectable Solution: Following intravenous use: occasional depression, lethargy, and fever. Following intra-articular (LEGEND Injectable Solution – 2 mL only) use: lameness, joint effusion, joint or injection site swelling, and joint pain.

®LEGEND is a registered trademark of Merial. ©2016 Merial, Inc., Duluth, GA. All rights reserved. EQUIOLG1607 (04/16)

1. Carmona JU, Prades M. Pathophysiology of osteoarthritis. Compendium Equine. 2009;4:28-40.
2. Freedom of Information Summaries for LEGEND.
3. LEGEND product label.