Help Reduce Your Horse’s Risk with the First-Ever Equine Leptospirosis Vaccine

Take the Leptospirosis Risk Assessment at and review your horse’s risk factors with your veterinarian. For every completed risk assessment, Zoetis will donate $1 to A Home for Every Horse.

Leptospirosis is a costly and under-diagnosed bacterial disease that can pose devastating health risks to horses. 

  • Exposure to Leptospira is common nationwide.1
  • Horses can become infected with leptospires through contact with urine from wildlife, cattle or dogs. Standing water and rainfall can pose an increased risk.

Should you be concerned about leptospirosis? Answer a few questions about your horse to find out.

Now you can help reduce your horse’s risk of leptospirosis with LEPTO EQ INNOVATOR, the first and only equine vaccine to help prevent leptospirosis in horses 6 months of age and older. LEPTO EQ INNOVATOR helps prevent leptospiremia caused by Leptospira interrogans serovar Pomona, which could, but has not been demonstrated to, help reduce the potential risk of equine recurrent uveitis (ERU), abortion or acute renal failure caused by L. pomona.*


  • It’s been estimated that up to 70% of all ERU cases are associated with Leptospira.2,3
  • $2.1 BILLION: the estimated economic impact of leptospiral-associated ERU in the U.S., including the cost of diagnosis, treatment and loss in horse value due to visual impairment or blindness.2-8
  • Up to 13% of equine bacterial abortions in endemic regions are caused by Leptospira.1
  • $102 MILLION: the estimated losses from leptospiral-associated abortions in Thoroughbred horses in Kentucky from 1993-2012.9

ACT NOW: Take the Leptospirosis Risk Assessment at and review your horse’s risk factors with your veterinarian.

*Currently, there are no vaccines available with USDA-licensed label claims against equine abortions, recurrent uveitis or acute renal failure due to L. pomona.

1. Divers, T.J.; Chang, Y-F. Leptospirosis. In: Robinson NE, Sprayberry KA, eds. Current Therapy in Equine Medicine. Vol 6. 6th ed. St. Louis, MO: Saunders Elsevier, 2009:145-147.
2. Polle F, Storey E, Eades S, et al. Role of intraocular Leptospira infections in the pathogenesis of equine recurrent uveitis in the southern United States. J Equine Vet Sci. 2014;34(11-12):1300-1306.
3. Borstel MV, Oey L, Strutzberg-Minder K, Boeve MH, Ohnesorge B. Direkter und indirekter Nachweis von Leptospiren aus Glasköperproben von Pferden mit ERU. Pferdeheilkunde. 2010;2(März/April):219-225.
4. Gerding JC, Gilger BC. Prognosis and impact of equine recurrent uveitis. Equine Vet J. In press. doi: 10.1111/evj.12451.
5. Faber NA, Crawford M, LeFebvre RB, Buyukmihci NC, Madigan JE, Willis NH. Detection of Leptospira spp. In the aqueous humor of horses with naturally acquired recurrent uveitis. J Clin Microbiol. 2000;38(7):2731-2733.
6. Dwyer AE, Kalsow CM. Visual prognosis in horses with uveitis, in Proceedings. Amer Soc Vet Ophthalmol Annu Meet 1998;1-8.
7. GAO. Horse Welfare: Action Needed to Address Unintended Consequences from Cessation of Domestic Slaughter. Available at: Published June 22, 2011. Accessed September 1, 2015.
8. Pick M, von Salis B, Schuele E, Schӧn P. Der Verkehrswert des Pferdes und seine Minderungen (“Value of horses and its depreciations”). 3rd ed. Berlin, Germany: Veterinärspiegel Verlag GmbH; 2012.
9. Carter CN, Cohen N, Steinman MN, Smith JL, Erol E, Brown S. Seroepidemiology of equine leptospirosis utilizing diagnostic laboratory specimens from 29 states (US) and one Canadian province, in Proceedings. 55th Annu AAVLD Meet 2012;51.

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